Epigenetic Control

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Featured Faculty

Professor Weiqun Peng

Dr. Peng's research interests center on statistical biological physics and computational biology.

Eukaryotic DNA is packaged into a highly organized chromatin structure with nucleosomes as the fundamental units. Chromatin in turn regulates the expression of genes encoded in the DNA. The study of gene regulation mediated by chromatin structure at the whole genome level is revolutionized with high throughput data generated by protocols based on next-generation sequencing. The signal extraction and data analysis has become a significant challenge. We developed a cutting-edge bioinformatic algorithm (SICER) for this purpose. It has been used widely in the community and incorporated into a number of popular analysis platforms ( e.g., Genomatix, Galaxy)

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